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Vitamins from the B complex, or also called B-Group vitamins, are a collection of water-soluble micronutrients. They form a vital nexus in the tapestry of human health. Comprising a spectrum of essential compounds, including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin), this group of vitamins plays a fundamental role in various biochemical processes. This article provides a comprehensive overview of the health benefits associated with B-Group vitamins, with a focus on their significance in pharmaceutical sciences.

What are the benefits of taking B complex vitamins?

B Complex Helps Energy Metabolism

B-Group vitamins serve as crucial cofactors in cellular energy metabolism. Through their participation in enzymatic reactions, especially in the breakdown of macronutrients, these vitamins facilitate the production of adenosine triphosphate (ATP), the energy currency of cells. Pharmaceutical professionals acknowledge the importance of B-Group vitamins in supporting metabolic pathways, making them indispensable in formulations targeting energy-related disorders.

Neurological Health

Several B vitamins, including B1, B6, B9, and B12, play pivotal roles in maintaining neurological health. Thiamine (B1) is vital for nerve function, pyridoxine (B6) is involved in neurotransmitter synthesis, folate (B9) contributes to DNA synthesis and repair, and cobalamin (B12) supports myelin formation. Understanding these roles is critical for pharmaceutical interventions addressing neurological conditions, from peripheral neuropathy to neurodegenerative disorders.

B Complex and Cardiovascular Health

B-Group vitamins, particularly B6, B9, and B12, play a key role in cardiovascular health. They contribute to the regulation of homocysteine levels, a marker associated with cardiovascular risk. Pharmaceutical professionals recognize the potential of B vitamins in formulations targeting cardiovascular diseases and consider their impact on preventive strategies.

Hematopoiesis and Anemia Prevention

Folate (B9) and cobalamin (B12) are essential for red blood cell formation and the prevention of megaloblastic anemia. Pharmaceutical considerations regarding hematopoiesis and anemia management necessitate a thorough understanding of the role of B-Group vitamins in these processes.

Skin and Hair Health

Biotin (B7) is renowned for its role in maintaining healthy skin, hair, and nails. In pharmaceutical formulations targeting dermatological conditions, the inclusion of biotin is a consideration for promoting skin health and addressing disorders such as alopecia.

Recommended daily dosing for B complex vitamins

It is a common fact that the B complex has multiple benefits for our health and nervous system, still, we have to be careful with the dosage. Here is the recommended daily intake (RDI):

  • Cobalamin (B12): 2.4 mcg;

  • Folate (B9): 400 mcg;

  • Biotin (B7): 30 mcg;

  • Pyridoxine (B6): 1.3 mg;

  • Pantothenic acid (B5):

  • Niacin (B3): 16 mg for men and 14 mg for women;

  • Riboflavin (B2): 1.3 mg for men and 1.1 mg for women;

  • Thiamine (B1): 1.2 mg for men and 1.1 mg for women.

NOTE: If you are pregnant or lactating, you may need higher amounts of B vitamins, also if you have a vitamin deficiency. Best consult your doctor and conduct the necessary blood test to determine your needs. Remember — food supplements are not a substitute for a varied diet.

What vitamins make up B complex?

The B complex supplements are one of the essential vitamins that our bodies require. They may help with some health problems. In our previous article “Why is the Vitamin B complex important?” The focus was on the benefits and dosage. There were mentioned all the eight main B vitamins and their influence on our organism. However, in this article we will take a look at each of them and what they are good for.

Cobalamin (vitamin B12)

This vitamin is useful for our blood and nerve cells, and also is helping the body to build healthy DNA structures. This is why it is good to take it during pregnancy as it supports fetal development. According to some sources, it may help if you suffer from anemia and can be used as a prevention of chronic disease, cancer, and anemia.

Folic Acid (B9)

Also known as folate (the natural form) is important for the DNA and genetic material. This is why doctors recommend the intake to start before pregnancy and to continue taking it after getting pregnant. It has a major role in women’s health, especially in reducing the risk of certain birth issues. It is also needed for the growth and for the production of red blood cells.

Biotin (vitamin B7)

Lots of people take to support the healthy growth of nails and hair. B7 is essential for the right functioning of our nerve system.

Pyridoxine (B6)

This vitamin helps the body in the process of making new red blood cells — they are responsible for transporting oxygen throughout the body. That vitamin is of major importance to our immune system, as it keeps it strong. It combines very well with vitamin D and magnesium during the cold seasons.

Pantothenic acid, also known as Vitamin B5

This vitamin promotes nervous system and brain health. It also helps in the process of reducing the cholesterol that our bodies produce.

Niacin (B3)

This vitamin along with B5 are both responsible for the production of hormones in the adrenal glands like stress and sex hormones. Vitamin B3 maintains the health of our digestion and nervous systems and skin. Doctors recommend it for improving cholesterol levels.

Riboflavin (B2)

Vitamin B2 has many functions. That vitamin is maintaining our nervous system, skin, and eyes healthy. It also plays a role in the process of turning the food into energy and helps enzymes in the body function properly. Moreover, it makes and repairs DNA, and is helping with the proper function of the digestive and nervous systems.

Thiamine (also known as Thiamine or vitamin B1)

This vitamin helps support our organs and their proper functioning. It is also important for healthy growth.

Who should take B complex supplements?

Vegetarians and vegans

As this way of feeding increases the risk of decreasing the B12 vitamin levels. This specific vitamins present in animal-based foods and meat. People who eat some dairy foods and eggs may be getting it from there. Still, it is good for levels to be measured by special blood tests and, if needed – to be taken additionally as a supplement.

Elderly people

Some researchers point out that low levels of cobalamin, folate, and pyridoxine may be associated with depression in older people. But that’s not all – some B vitamins are slowing down the cell’s aging process.

People who are taking specific medications, as can lead to deficiency in B vitamins. For example, birth control pills can affect several B vitamins, including B2, B6, B9, and B12.  Also, the intake of B complex is very important during pregnancy and nursing. Especially if you are pregnant, folate (B9) and cobalamin (B12) are necessary to support fetal development.


B-Group vitamins emerge as pivotal players in maintaining human health across diverse physiological systems. From energy metabolism to neurological function, cardiovascular health, hematopoiesis, and dermatological well-being, the therapeutic potential of B-Group vitamins in pharmaceutical sciences is vast. A nuanced understanding of their roles is essential for healthcare professionals seeking to harness the benefits of B vitamins in optimizing patient outcomes through targeted pharmaceutical interventions.


As a service to our readers, MVS Pharma GmbH publishing provides access to our library of archived content — in our blog. Please note the date of last review or update on all articles. No content on this site, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

Dr. Disha Trivedi

Dr. Disha Trivedi is PhD in Molecular Genetics and Biotechnology. She is working as a medical writer and researcher at MVS Pharma GmbH.