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The oxidation of omega-3-rich oils, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), is a critical factor influencing the quality, stability, and consumer acceptance of these products. Oxidized oils can lead to unpleasant fishy odors and tastes, limiting their appeal. This article explores oxidation factors, testing methods, and industry best practices for maintaining oil freshness.

Key Factors Affecting Oxidation

Oxidation rates in omega-3 oils are influenced by:

  • Exposure to oxygen, light, and heat – Accelerates oxidative reactions.
  • Degree of unsaturation – EPA and DHA, being highly unsaturated, are particularly prone to oxidation.
  • Storage conditions – Proper handling and packaging can slow oxidation.

To mitigate oxidation, manufacturers implement strategies such as:

  • Using antioxidants (e.g., tocopherols) to slow oxidation.
  • Minimizing oxygen exposure during production.
  • Refining oils under vacuum to remove oxygen-sensitive compounds.
  • Packaging in inert gases (e.g., nitrogen) to prevent oxidation.

Consumer Insights on Omega-3 Taste

A survey conducted across nine countries (Australia, Brazil, China, France, UK, USA, Russia, Germany, Japan) found that taste remains a major barrier to omega-3 consumption:

  • 7%-23% of non-users cite the fishy taste as a deterrent.
  • 18% of U.S. consumers stop taking omega-3 supplements due to fishy burps.

Measuring Oxidation in Omega-3 Oils

Oxidation is primarily assessed through:

  • Peroxide Value (PV): Measures peroxides, the first indicator of oxidation.
  • p-Anisidine Value (pAV): Assesses secondary oxidation products such as aldehydes.
  • Sensory Evaluation: A simple taste and smell test can indicate rancidity.

However, some methods have limitations. For example, the pAV test is unreliable for oils containing strong pigments like krill or virgin salmon oil due to carotenoid interference.

Industry Standards and Findings

The omega-3 industry has implemented strict oxidation limits:

  • 94-98% of omega-3 products meet regulatory oxidation standards.
  • Studies confirm that modern manufacturing techniques effectively reduce oxidation levels.

Application of Research Findings at MVS Pharma GmbH

Bioavailability and Oxidation Protection

MVS Pharma has integrated these research insights into the development of MVS Omega-3 Capsules, focusing on:

  • Norwegian Premium Quality: Deodorized re-esterified triglyceride (rTG) concentrates.
  • High Bioavailability: Minimum 90% triglycerides for optimal absorption.
  • Optimized EPA/DHA Ratios:
  • EPA (Eicosapentaenoic Acid C20:5): 480 mg/g
  • DHA (Docosahexaenoic Acid C22:6): 320 mg/g
  • DPA (Docosapentaenoic Acid C22:5): 43 mg/g

Studies suggest DPA enhances cardiovascular and neural health, with effects similar to EPA and DHA.

Oxidation Control Measures

Our formulation includes:

  • Natural Tocopherols (3.8 mg/g) to minimize oxidation.
  • Total Oxidation Value: 4 (max allowed: 10).
  • Peroxide Value: 0.1 meq/kg (max: 1.2 meq/kg).
  • Anisidine Value: 4 (max: 8).

Purity & Heavy Metal Testing

MVS Pharma ensures safety through advanced molecular distillation, removing:

  • Heavy metals (Arsenic, Cadmium, Lead, Mercury).
  • Environmental pollutants (Dioxins, PCBs).

All tests confirm full compliance with safety standards.

Enhancing Consumer Experience

To improve sensory acceptance, MVS Pharma employs:

  • Encapsulation technology to prevent fishy burps.
  • Innovative packaging with fully recyclable, BPA-free, double-layer protection (no aluminum foil or solvent adhesives).

Conclusion

Research confirms that oxidation management is critical in maintaining omega-3 product quality. MVS Pharma applies these insights to produce premium omega-3 capsules with high bioavailability, minimal oxidation, and optimal purity.

References

Disclaimer:

As a service to our readers, MVS Pharma GmbH publishing provides access to our library of archived content — in our blogPlease note the date of the last review or update on all articles. No content on this site should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

MVS Pharma GmbH will soon be launching an omega-3 dietary supplement onto the European market that has been developed for the highest quality standards in terms of oxidation avoidance and therefore greatest bioavailability. In addition, in vitro studies are currently underway at the University of Ulm, in which Professor Dr. Rüdiger Groß tested a patented mouth and nose spray (Virudol) that can eliminate various flu viruses based on natural substances. In addition, MVS has a wholesale license and has specialized in sourcing much-needed medicines such as Amoxicillin, Salbutamol, etc. from India through its local branch with a focus on local quality and safety testing, compliance with international GMP regulations and the highest quality level of user security (examples of local language brochures, identical units of measurement, batch control and full tracking, etc.).

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