Nitric oxide – The Miracle Molecule. Labelled as a ‘molecule of the year’… Let’s learn more about it.
Coronavirus, is spreading around the world nore than a year. New COVID-19 variants are coming along, and morbidity & mortality constantly changing. Discovering a substance that can stop all of those, is definitely good news. We’re more than tired and exhausted of lockdowns and restrictions, so the only question is: could it be the big solution? Is this for real?
But let me share some history first. .
It was successfully used on newborn babies, suffering from heart defects and acute respiratory distress syndrome (ARDS), also on adults.
Another coronavirus – SARS-COV-1, outbreaked back in 2003, shows wide similarities with present SARS-COV-2. Patients with SARS-COV-1 were treated with NO back then.
This might also be an advantage and solution. Especially when it comes to the suspicions of possible link between AstraZeneca vaccine and brain clots’ . We all have heard about the side effects after getting the vaccine.
A healthy person`s arterial oxygen partial pressure ratio has to be 400 mmHg . So patients with a lower level must receive extra oxygen through a nasal cannula or mask. The lipophilic molecule of inhaled NO is spreading across the pulmonary membranes of the infected cells.
It helps boosting the blood-oxygen saturation level. The main goal is cutting down numbers of patients’ needs of respiratory breathing , they’re already in a short supply in some countries.
During the past year, multiple researches have been made with COVID-19 patients, that were suffering from severe pneumonia. They were with inhaled nitric oxide (iNO). So far all results are quite promising.
International study overseen by Massachusetts General Hospital (MGH) already took place in Massachusetts, Alabama, Louisiana, Sweden and Austria. They’ve been testing patients with mild to moderate cases of the coronavirus through a CPAP breathing machine of iNO for 20-30 minutes twice a day for two weeks.
MGH reviewed a second trial on health workers, exposed to coronavirus patients on a daily basis. All of them were using a high dose of iNO for 10 to 15 minutes at the start and end of every shift.
Uppsala University, Sweden and Karolinska Institute based their study on a discovery that took effect in 2003 SARS. They used NO released from S-Nitroso-N-acetylpenicillamine (SNAP) and its effect grew stronger, as they raised the dose.
While vaccine deliveries are under discussion, hospitals are struggling with COVID-19 patients in need of immediate oxygenation. iNO is the best treatment, found during the pandemic outbreak.
So far, nitric oxide is saving lives and it’s only a matter of time to be included as a most-commonly used and available substance.
Liliya Ganeva is an article writer, who explores all the actual, up-to-date COVID-19 information, and the possibilities for producing aerosols made out of plants against respiratory viruses and bacteria.