Virudol ™ is an antiviral system consisting of a Mouth-Nose Spray and a Ventilation Component for rooms. It was developed to prevent the transmission of infectious diseases, especially the risk of coronavirus disease (Covid-19).
It contains natural substances that bind tightly to virus particles, they attach especially to the spike proteins. The additional components mask the virus and inhibit the binding of the viral particles to the cell receptor. Subsequently, the infection of human cells is blocked, and the replication and proliferation of infectious particles are restrained.
The inhibitors are of vegetable origin, they are obtained from the peel of citrus fruits. These active ingredients are also used as natural ingredients in food, cosmetics, and beverages. They have long been known in the literature to have antiviral activities. This was also shown by molecular docking experiments with SARS-CoV-2. In the concentrations used, they are harmless to humans. In addition, the oral/nasal sprayVirudol™ contains a surface-forming substance that forms a thin film on the mucous membranes of the mouth and nose. In this way, the active ingredients remain present for a certain time and the attachment of SARS-CoV-2 to the ACE2 receptor is prevented for a long time. The protection works in two ways: For infected people who can breathe out the virus this is inhibited and for people who could breathe in the viral particles, these are masked, and infection is hindered.
A second important aspect is that the spray bottle, which will contain these natural substances has to be so innovative that spraying into the mouth and nose is only a matter of the finest nebulization. Meaning there will be no droplets or a jet that can be very uncomfortable to use. In addition, the requirement was not to use any preservatives in order not to limit the naturalness and possibly multiple use. Durability and protection against heat should also be guaranteed. This was solved by an additional inner bag in the bottle, which contains the actual substance.
In this way, a fully preventive spray is formulated that aims at protecting against the transmission of SARS-CoV-2.